Funded projects

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  Jean Yu Lim

  University of Auckland

  Doctoral scholarship - $166,174 - Funding Round: 2024 B

  Uncovering the mechanisms of immune cell aging in dementia

  Dementia is a disease of aging, but we don’t fully understand the difference between normal and diseased aging. Microglia, the brain’s immune cells, become prematurely aged in dementia and accumulate to harm other brain cells. We now need to uncover the mechanisms behind this premature cell aging to safeguard the brain from neurodegeneration. This project will use human brain cells and tissue to understand more about the abnormal aging of microglia in dementia and discover new drug targets, ultimately transforming the treatment of dementia.