Funded projects

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  Professor Anne La Flamme

  Te Herenga Waka Victoria University of Wellington

  Project grant - $211,400 - Funding Round: 2025 A

  Regulating chemokine networks in the central nervous system

  This research explores a new treatment approach for brain inflammation seen in diseases like multiple sclerosis (MS). It focuses on Tet-29, a synthetic molecule that helps regulate immune cell movement into the brain, reducing harmful inflammation while allowing normal immune function. Using animal models, the study will examine how Tet-29 interacts with specific chemical signals that guide immune cells. The goal is to develop safer therapies that target just the damaging immune responses while maintaining the healthy ones, potentially benefiting people with neuroinflammatory conditions such as MS, Alzheimer’s disease, and traumatic brain injury.